Background: Presynaptic forms of congenital myasthenic syndromes (CMS) due to pathogenic variants in SLC18A3 impairing the synthesis and recycling of acetylcholine (ACh) have recently been described.SLC18A3 encodes the vesicular ACh transporter (VAChT), modulating the active transport of ACh at the neuromuscular junction, and homozygous loss of VAC
A voluntary upper respiratory biosurveillance program in the USA received 9740 nasal swab submissions during the years 2008–2021 from 333 veterinarians and veterinary clinics.The nasal swabs were submitted for qPCR testing for six common upper respiratory pathogens:equine influenza virus (EIV), equine herpesvirus-1 (EHV-1), equine herpesvirus-4 (
Although sports officials are essential in the adjudication of rules during competitions, research into officiating populations is preliminary.This review explores existing research on the effects of sleep loss on decision-making in athlete populations, to gain relevant Snow Cone Maker insight into sports officials and the growing decision-making d
The two PEACE (Plasma Electron And Current Experiment) sensors on board each Cluster spacecraft sample the electron velocity distribution across the full 4<pi> solid angle and the energy range 0.7 eV to 26 keV with a time resolution of 4 s.We present high energy and angular resolution 3D observations of electrons of spacecraft origin in the v
Background: There are many techniques being followed in marital or couples therapy for the resolution of marital discord.In the particular module of Conjoint collaborative therapy Snow Cone Maker where joint sessions with the couple run concurrently with individual sessions for each partner, an additional issue crops up which may influence the outc